ea0041ep900 | Pituitary - Clinical | ECE2016
Muhammad Ammar
, Ficarra Gianluca
, Franck Sanne
, Nazarri Elena
, Tagliafico Alberto
, Neggers Sebastian
, Ferone Diego
, Gatto Federico
Background: Acromegaly is a severe systemic condition characterized by elevated circulating levels of growth hormone (GH) and insulin-like growth factor I (IGF-I) and increased mortality and morbidity. The role of GH and IGF-I in mammary hyperplasia is well established and GH/IGF-I elevation has been hypothesized to favor neoplastic development. We recently demonstrated that premenopausal females with active acromegaly may display an increased mammographic breast density (MBD)...